My amp goes to 13!

My amp goes to 13!
My amp goes to 13!

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Santa came early to my house!

A 2013 Gibson Les Paul Future Tribute and a Peavey Vypyr Vip 2.

It's going to take me a while to figure out what all those knobs, buttons and blinking lights on the amp do.
Santa came early to my house!

A 2013 Gibson Les Paul Future Tribute and a Peavey Vypyr Vip 2.

It’s going to take me a while to figure out what all those knobs, buttons and blinking lights on the amp do.

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Elsevier is using DMCA to block authors from sharing their own work

Better to just publish in PLOS.

http://svpow.com/2013/12/06/elsevier-is-taking-down-papers-from-academia-edu/

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Elsevier is taking down papers from Academia.edu
Lots of researchers post PDFs of their own papers on their own web-sites. It’s always been so, because even though technically it’s in breach of the copyright transfer agreements that we blithely s…

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Happiness is

Watching my Saturn bitcoin miner from kncminer.com running at 312 GHps.

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Married white male desperately seeking:

An efficient algorithm to search an extended DNA sequence for motifs occurring within a window of a given size with a given frequency (in other words, an algorithm to detect motif clumping).

I wrote a brute force algorithm, but I'm afraid if I throw it at the e. coli genome it will kill my shiny new computer. To say nothing of the human genome.

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Goodbye Lou

The Velvet Underground – Heroin

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Another article I stumbled upon in my morning surfing.  It's an interesting…

Another article I stumbled upon in my morning surfing.  It's an interesting idea, instead of life beginning in an "RNA world" which is thermodynamically improbable, it may have begun in a "peptide-RNA world" where peptides and RNA co-evolved.  Apparently the primordial peptides would eventually evolve into the amino-acyl tRNA sythetases, important enzymes that determine the genetic code in all living things today.  It's an attractive idea since it becomes easier to see how these early interactions of peptides and RNA might eventually evolve into the genetic code.

http://www.jbc.org/content/288/37/26864

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Casting Doubt on the RNA World Hypothesis♦

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I got excited when I read the headline, but as usual it's sensationalistic

 

What I gather from the article, all they're doing is using their knowledge of genetic inheritance to allow a more informed mate decision.  

Apparently this is illegal in Canada.  Why?  On some level everyone does this when they look for a mate don't they?  He likes blue eyes, she likes blond hair, etc.  It's just selection.  It's been going on as long as humanity has existed.  23andMe is just making it more informed.

Maybe it's because they're keeping a database of peoples genes?  Maybe because they also look at disease susceptibility genes?  I don't know, but it doesn't seem like a big deal to me.

http://www.theverge.com/2013/10/2/4795586/23andme-designer-baby-patent

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23andMe receives patent to create designer babies, but denies plans to do so
Thanks to personal genomics companies like 23andMe, it’s becoming quicker and easier for us to find out who we are. But will the same technology one day allow us to decide who our babies will be…

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Aha, I was wondering why bitcoin prices crashed then almost immediately rebounded…

Aha, I was wondering why bitcoin prices crashed then almost immediately rebounded yesterday evening. 

I think this can be nothing but good for the bitcoin economy in the long run.  The Silk Road may have provided some small proportion of the demand for bitcoins, so prices may drop in the short term.  Longer term though, now that the infamous illegal marketplace is gone, it should make bitcoins seem more legitimate and hopefully help to increase adoption.  And maybe some legislators who've been afraid of bitcoins and have threatened to regulate them, will finally realize that they're not so scary after all.

http://www.theverge.com/2013/10/2/4794780/fbi-seizes-underground-drug-market-silk-road-owner-indicted-in-new

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FBI seizes underground drug market Silk Road, owner indicted in New York
It appears the Federal Bureau of Investigation has finally cracked down on Silk Road, the underground marketplace where users could buy cocaine, heroin, meth, and more using the virtual currency…

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Camp 31 in Paris, Ontario – apparently the best ribs this side of Alabama

I'm a believer.
Camp 31 in Paris, Ontario – apparently the best ribs this side of Alabama. I’m a believer.

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